HAI-score: An Objective AI Method for Accurate HER2 H-score Estimation in Breast Cancer
Published in ASCO Conference, 2025, 2025
Accurate HER2 scoring is critical for guiding targeted therapy in breast cancer, yet manual estimation suffers from subjectivity and variability.
We present HAI-score, an explainable and reproducible AI pipeline that quantifies HER2 H-scores directly from IHC-stained slides.
Our method outperformed traditional assays and demonstrated strong correlation with clinical outcomes across multi-institutional cohorts.
Citation
Nasser, S., et al. “HAI-score: An Objective AI Method for Accurate HER2 H-score Estimation in Breast Cancer.” Journal Publication, June 2025.